Category Archives: Infections

Preemptive antiviral therapy started within 2-6 weeks after transplantation has the advantage of a relatively low VL and the absence or minimal evidence of histologic recurrence, but is limited by tolerability, particularly in patients with high MELD scores pre-transplantation. Rates … Continue reading →

Regarding the calcineurin inhibitors (CNI), most of the studies suggest that there is no significant difference between tacrolimus and cyclosporine with respect to their impact on histologically diagnosed HCV recurrence and graft or patient survival (Iacob 2007, Berenguer 2007). Cyclosporine … Continue reading →

Many factors such as donor and host characteristics, virologic features and immunosuppression have been shown to influence the progression of post-transplant liver disease. Viral factors. As early as the first week postoperatively, the HCV RNA level increases 10- to 20-fold … Continue reading →